Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | AANAT | Q16613 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12712632 | 0.80 | MEN1 (0.74) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL13609793 | 0.76 | MEN1 (0.77) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL468850 | 0.74 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL29669230 | 0.73 | MEN1 (0.97) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6424908 | 0.72 | AANAT (1.00) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL12059105 | 0.72 | MEN1 (0.73) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL20648007 | 0.72 | MTNR1A (0.71) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL5841251 | 0.72 | MEN1 (0.74) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL13576444 | 0.71 | MEN1 (0.68) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL20017955 | 0.71 | HTR2A (0.58) | MEN1KMT2ALMNACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3348556-A1 | HETEROARYL AMIDES AS INHIBITORS OF PROTEIN AGGREGATION | UCB Biopharma SPRL (BE) | 2018-07-18 | — | — | EP | disclosed |