Nb-Acetyltryptamine

Nb-Acetyltryptamine

SCHEMBL468850

CC(=O)NCCc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
CYP1A2 P05177 2/20 1.00
BLM P54132 2/20 1.00
LMNA P02545 1/20 1.00
PKM P14618 1/20 1.00
TSHR P16473 1/20 1.00
CYP2C19 P33261 1/20 1.00
MMP9 P14780 1/20 0.70
AANAT Q16613 1/20 0.70
NPC1 O15118 1/20 0.70
RAB9A P51151 1/20 0.70
MTNR1A P48039 5/20 0.68
MTNR1B P49286 4/20 0.68
NOTUM Q6P988 2/20 0.68
KDM4E B2RXH2 1/20 0.68
ALDH1A1 P00352 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2D6 P10635 1/20 0.68
MAPT P10636 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nb-Acetyltryptamine SCHEMBL29669230 0.98 MEN1 (0.97) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL4704852 0.90 MEN1 (0.82) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL13609793 0.87 MEN1 (0.77) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL6394942 0.86 MEN1 (0.76) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL761155 0.85 MTNR1A (0.76) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL20927525 0.85 MEN1 (0.74) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL31114206 0.85 MTNR1A (0.76) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL761706 0.85 MEN1 (0.75) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL5841251 0.85 MEN1 (0.74) MEN1KMT2ACYP1A2BLMLMNA
SCHEMBL627038 0.85 MEN1 (0.74) MEN1KMT2ACYP1A2BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595497-B2 Processes for the production of tryptamines COMPASS PATHFINDER LIMITED (GB) 2026-04-07 US claimed
CN-118791419-A N-acetyltryptamine compound, composition and application 南华大学 2024-10-18 CN claimed
CN-117304090-A Amide compounds with plant regulation activity, and preparation and application thereof 中国科学院兰州化学物理研究所 2023-12-29 CN claimed
CN-116904348-A Streptomyces sp.P-10 marine Streptomyces and application thereof 厦门大学 2023-10-20 CN claimed
US-20210108238-A1 PROCESSES FOR THE PRODUCTION OF TRYPTAMINES HERCULES CAPITAL, INC. 2021-04-15 US claimed
CN-112105734-A Method for producing tryptamine 新图集生物技术有限责任公司 2020-12-18 CN claimed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
US-20200046693-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-02-13 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO claimed
WO-1994013686-A1 GLYCOSYL PHOSPHOTRIESTER DERIVATIVES AND THEIR UTILIZATION FOR THE CENTRAL NERVOUS SYSTEM INSTITUT PASTEUR (FR) 1994-06-23 WO claimed
EP-0246910-B1 Coated veterinary implants HOECHST VETERINAER GMBH (DE) 1994-03-16 EP claimed
US-5283343-A Melatonin antagonists WHITBY RESEARCH, INC. (US) 1994-02-01 US claimed
EP-0375726-A4 MELATONIN ANALOGUES 1991-01-30 EP claimed
EP-0375726-A1 MELATONIN ANALOGUES Whitby Research Incorporated (US) 1990-07-04 EP claimed
US-4882137-A MELATONIN GENE LINK AUSTRALIA LIMITED (AU) 1989-11-21 US claimed
WO-1989001472-A1 MELATONIN ANALOGUES NELSON RESEARCH & DEVELOPMENT CO. (US) 1989-02-23 WO claimed
EP-0246910-A2 Coated veterinary implants Hoechst Veterinär GmbH (DE) 1987-11-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595497-B2 Processes for the production of tryptamines INMT, TPH1, TPH2 MEN1 2840/4885KMT2A 1817/4885CYP1A2 313/4885
US-20200046693-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ZELLWEGER SPECTRUM DISORDER HSD17B4, CYP27A1, OAT MEN1 3163/4885KMT2A 1938/4885CYP1A2 2458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.