Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279486 | 0.79 | MGLL (0.59) | MGLLFAAHNPC1RAB9AMAOA | |
| SCHEMBL15881350 | 0.79 | NPC1 (0.60) | MGLLFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21237811 | 0.78 | ALDH1A1 (0.49) | FFAR4NPC1RAB9ASMN1; SMN2PTGDR2 | |
| SCHEMBL27601834 | 0.76 | MGLL (0.56) | MGLLFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4748097 | 0.73 | RAB9A (0.66) | FAAHNPC1RAB9A | |
| SCHEMBL250728 | 0.73 | MAOA (0.53) | NPC1RAB9AHRH3MAOAKCNH2 | |
| SCHEMBL22680616 | 0.73 | MAOA (0.53) | NPC1RAB9AHRH3MAOAKCNH2 | |
| SCHEMBL4435567 | 0.73 | TAAR1 (0.50) | HTR2CHTR2BFFAR4FAAHNPC1 | |
| SCHEMBL12072841 | 0.73 | HTR2C (0.53) | HTR2CHTR2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28104032 | 0.72 | HDAC8 (0.56) | FAAHNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136935-A1 | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2018-07-26 | — | — | WO | disclosed |