Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.53 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040786 | 1.00 | P4HB (0.53) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL16847902 | 1.00 | P4HB (0.53) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL11154076 | 0.88 | MEN1 (0.56) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL2037083 | 0.87 | POLB (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL13347802 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL15040782 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL17366230 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL2039373 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL16847549 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 | |
| SCHEMBL6410787 | 0.86 | LMNA (0.58) | P4HBPDIA4PDIA3MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960247-A1 | PHENYL-ALPHA-D-MANNOSIDES FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS CAUSED BY ESCHERICHIA COLI | University of Basel (CH) | 2015-12-30 | — | — | EP | disclosed |
| CN-102753562-B | As the mannose derivative of bacterial adhesion antagonist | UNIVERSITAT BASEL (CH) | 2015-11-25 | — | — | CN | disclosed |
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIV BASEL (CH) | 2015-06-25 | — | — | US | disclosed |
| EP-2604619-A2 | Mannose derivatives as antagonists of bacterial adhesion | University of Basel (CH) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012164074-A1 | MANNOSE PHOSPHATE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-12-06 | — | — | WO | disclosed |
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2012-10-25 | — | — | US | disclosed |
| EP-2513128-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | University of Basel (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073112-A2 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | UNIVERSITY OF BASEL (CH) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270824-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | P4HB 1907/4885PDIA4 3309/4885PDIA3 2047/4885 |
| US-20150175644-A1 | MANNOSE DERIVATIVES AS ANTAGONISTS OF BACTERIAL ADHESION | MAN2A1, MANBA, M6PR | P4HB 1907/4885PDIA4 3309/4885PDIA3 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.