Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406475 | 0.84 | KMT2A (0.40) | RORCMEN1KMT2AP2RY1PDE10A | |
| SCHEMBL18661502 | 0.83 | PDE10A (0.39) | RORCMEN1KMT2ADRD1PDE10A | |
| SCHEMBL20406468 | 0.79 | P2RY1 (0.35) | RORCDRD1P2RY1 | |
| SCHEMBL20406479 | 0.77 | MEN1 (0.35) | MEN1KMT2AP2RY1ELANE | |
| SCHEMBL20406690 | 0.75 | PDE10A (0.38) | RORCMEN1KMT2APDE10A | |
| SCHEMBL20406792 | 0.73 | PDE10A (0.36) | PDE10AGPBAR1 | |
| SCHEMBL20394318 | 0.73 | PDE10A (0.38) | MEN1KMT2APDE10A | |
| SCHEMBL20406590 | 0.73 | FEN1 (0.37) | RORC | |
| SCHEMBL20406375 | 0.73 | P2RY1 (0.39) | RORCDRD1P2RY1PDE10A | |
| SCHEMBL20406391 | 0.73 | MEN1 (0.46) | MEN1KMT2AP2RY1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |