SCHEMBL20409663

SCHEMBL20409663

CC1(C)CN=C(c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cn2)O1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 2/20 0.35
ENPP3 O14638 1/20 0.35
MAPK1 P28482 2/20 0.33
PTPN11 Q06124 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
MAPK3 P27361 1/20 0.33
CNR2 P34972 1/20 0.33
CYP11B1 P15538 3/20 0.32
CYP11B2 P19099 3/20 0.32
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
DHFR P00374 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TP53 P04637 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20409958 0.89 CNR2 (0.38) CNR2
SCHEMBL20409651 0.86 ENPP3 (0.36) ENPP1ENPP3MAPK1PTPN11CA12
SCHEMBL20409619 0.85 CNR2 (0.35) MAPK1CNR2CYP11B1CYP11B2NPC1
SCHEMBL20409672 0.82 KDM4E (0.35) ENPP1ENPP3MAPK1PTPN11NPC1
SCHEMBL20409647 0.81 CHRNA1 (0.38) ENPP1ENPP3MAPK1CA12CA9
SCHEMBL20409665 0.81 ENPP1 (0.36) ENPP1ENPP3MAPK1PTPN11CA12
SCHEMBL20409970 0.81 CNR2 (0.36) CNR2
SCHEMBL20409662 0.80 KDM4E (0.48) ENPP1ENPP3MAPK1PTPN11MAPK3
SCHEMBL20409722 0.80 CNR2 (0.33) MAPK1CNR2CYP11B1CYP11B2MAPT
SCHEMBL20409911 0.78 CNR2 (0.34) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SK MATERIALS JNC CO., LTD. (KR) 2022-05-24 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME JNC CORPORATION (JP) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SLC7A5, EML4, ARNT ENPP1 3858/4885ENPP3 3900/4885MAPK1 901/4885
US-20180212156-A1 AZOLINE RING-CONTAINING COMPOUND, ELECTRON TRANSPORT/INJECTION LAYER MATERIAL CONTAINING THE SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SLC7A5, EML4, ARNT ENPP1 3858/4885ENPP3 3900/4885MAPK1 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.