Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAC2 | P15153 | 1/20 | 0.30 |
| ▸ | RAC3 | P60763 | 1/20 | 0.30 |
| ▸ | CDC42 | P60953 | 1/20 | 0.30 |
| ▸ | RAC1 | P63000 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19269229 | 0.97 | NPY5R (0.32) | TSPOATMNPY5RICMTTP53 | |
| SCHEMBL19269223 | 0.97 | NPY5R (0.32) | TSPOATMNPY5RICMTTP53 | |
| SCHEMBL19269236 | 0.97 | NPY5R (0.33) | TSPOATMNPY5RICMTTP53 | |
| SCHEMBL19269228 | 0.96 | TSPO (0.34) | TSPOATMNPY5RICMTTP53 | |
| SCHEMBL19269924 | 0.94 | ICMT (0.35) | ATMICMTTP53BRD4 | |
| SCHEMBL19270765 | 0.93 | ATM (0.36) | ATMICMTTP53BRD4 | |
| SCHEMBL19270046 | 0.90 | ATM (0.33) | TSPOATMNPY5RICMTRAC2 | |
| SCHEMBL19270017 | 0.89 | RAC2 (0.31) | TSPOATMTP53RAC2RAC3 | |
| SCHEMBL19268561 | 0.86 | ATM (0.33) | ATMNPY5RICMTRAC2RAC3 | |
| SCHEMBL19269982 | 0.86 | TSPO (0.33) | TSPONPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | TSPO 3985/4885ATM 3591/4885NPY5R 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.