Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.48 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 2/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419169 | 0.90 | HSPA8 (0.58) | HSPA5HSPA8RXFP1DOT1LCDK5 | |
| SCHEMBL20419330 | 0.90 | HSPA8 (0.58) | HSPA5HSPA8RXFP1DOT1LCDK5 | |
| SCHEMBL20419188 | 0.77 | HSPA8 (0.39) | HSPA5HSPA8RXFP1DOT1LCDK1 | |
| SCHEMBL6380760 | 0.76 | HSPA8 (0.61) | HSPA5HSPA8RXFP1ADKDOT1L | |
| SCHEMBL1740449 | 0.75 | HSPA5 (0.63) | HSPA5HSPA8RXFP1ADKDOT1L | |
| SCHEMBL20419157 | 0.73 | HSPA5 (0.61) | HSPA5HSPA8RXFP1ADKDOT1L | |
| SCHEMBL14853733 | 0.71 | ADORA3 (0.80) | DOT1LSLC28A2ADORA3SMN1; SMN2DPP4 | |
| SCHEMBL16341965 | 0.71 | ADORA3 (0.80) | DOT1LSLC28A2ADORA3SMN1; SMN2DPP4 | |
| SCHEMBL14946319 | 0.71 | ADORA3 (0.80) | DOT1LSLC28A2ADORA3SMN1; SMN2DPP4 | |
| SCHEMBL4463234 | 0.71 | ADORA3 (0.80) | DOT1LSLC28A2ADORA3SMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |