Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 3/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419330 | 0.80 | HSPA8 (0.58) | HSPA8HSPA5RXFP1CDK1CCNB1 | |
| SCHEMBL20419169 | 0.80 | HSPA8 (0.58) | HSPA8HSPA5RXFP1CDK1CCNB1 | |
| SCHEMBL20419183 | 0.77 | HSPA5 (0.48) | HSPA8HSPA5RXFP1CDK1CDK2 | |
| SCHEMBL30870546 | 0.71 | ADORA3 (0.62) | SLC28A2HIF1AADORA2ASMN1; SMN2DPP4 | |
| SCHEMBL6380760 | 0.67 | HSPA8 (0.61) | HSPA8HSPA5RXFP1CDK1CCNB1 | |
| SCHEMBL1740449 | 0.66 | HSPA5 (0.63) | HSPA8HSPA5RXFP1CDK1CCNB1 | |
| SCHEMBL19038496 | 0.65 | ADORA2A (0.61) | HSPA8HSPA5RXFP1ADORA2AADORA3 | |
| SCHEMBL20419157 | 0.65 | HSPA5 (0.61) | HSPA8HSPA5RXFP1CDK1CCNB1 | |
| SCHEMBL6839954 | 0.65 | ADORA2A (0.60) | HSPA8HSPA5RXFP1ADORA2AADORA3 | |
| SCHEMBL6840004 | 0.64 | HSPA8 (0.60) | HSPA8HSPA5RXFP1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |