Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 9/20 | 0.43 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419168 | 1.00 | CDK2 (0.49) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL20419165 | 0.80 | RAPGEF3 (0.49) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL20917327 | 0.80 | RAPGEF3 (0.49) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL20419136 | 0.80 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL20419234 | 0.80 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL3704527 | 0.80 | NADK (0.57) | HSPA8HIF1A | |
| SCHEMBL3701954 | 0.80 | NADK (0.57) | HSPA8HIF1A | |
| SCHEMBL20938262 | 0.80 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL20419191 | 0.80 | RAPGEF3 (0.49) | CDK2CCNA2CCNA1CDK1CCNB1 | |
| SCHEMBL20419180 | 0.80 | ADORA3 (0.52) | CDK2CCNA2CCNA1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |