SCHEMBL20421656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20421627	0.84	ALDH1A1 (0.54)	ALDH1A1HPGDPARP14HSD17B10MAOA
	SCHEMBL20436302	0.81	SMN1; SMN2 (0.49)	ALDH1A1HPGDTSHRLMNAGAA
	SCHEMBL10805152	0.80	HSD17B10 (0.54)	ALDH1A1HPGDNPSR1HSD17B10MAOA
	SCHEMBL20436310	0.78	NLRP3 (0.36)	ALDH1A1HPGDNPSR1HSD17B10LMNA
	SCHEMBL20436303	0.76	MGLL (0.46)	ALDH1A1HPGDNPSR1GAAKMT2A
	SCHEMBL9350593	0.75	HSD17B10 (0.47)	ALDH1A1HPGDNPSR1HSD17B10TSHR
	SCHEMBL20421679	0.75	ALDH1A1 (0.59)	ALDH1A1HPGDPARP14HSD17B10MAOA
	SCHEMBL20436308	0.74	ITGB3 (0.64)	ALDH1A1NPSR1TSHRGAAMAPK1
	SCHEMBL20436328	0.73	ACE (0.37)	ALDH1A1HPGDHSD17B10LMNAGAA
	SCHEMBL20421624	0.72	CD44 (0.42)	ALDH1A1HPGDHSD17B10TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.