SCHEMBL20424715

SCHEMBL20424715

COc1ccc(C(N[S+]([O-])C(C)(C)C)c2ccc(C)o2)c(N2CC3CC3C2)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ HCRTR1 O43613 1/20 0.30
▸ HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20424799 0.88 — —
SCHEMBL20424427 0.87 KMT2A (0.38) —
SCHEMBL20424598 0.86 HTT (0.32) —
SCHEMBL20424582 0.86 PRKDC (0.39) —
SCHEMBL20424617 0.84 FFAR1 (0.32) —
SCHEMBL20424835 0.81 PKM (0.36) —
SCHEMBL20424637 0.81 PKM (0.36) —
SCHEMBL23683833 0.78 PKM (0.35) HCRTR1HCRTR2
Hydrochloric Acid SCHEMBL20424938 0.77 MAPT (0.36) HCRTR1HCRTR2
SCHEMBL20424623 0.75 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573972-B1 RORGAMMA MODULATORS AND USES THEREOF GENFIT (FR) 2026-01-14 — — EP disclosed
US-11077115-B2 Rorgamma modulators and uses thereof GENFIT (FR) 2021-08-03 — — US disclosed
WO-2018138359-A1 RORGAMMA MODULATORS AND USES THEREOF GENFIT (FR) 2018-08-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077115-B2 Rorgamma modulators and uses thereof RORB, RORC, RORA HCRTR1 1238/4885HCRTR2 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback