Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29964263 | 1.00 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL6603490 | 0.81 | TDP1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL3222257 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL10410990 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL3222249 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL8948080 | 0.81 | TDP1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380625 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380608 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380623 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380589 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138369-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | CHEMCOM S.A. (BE) | 2018-08-02 | — | — | WO | claimed |
| US-20220378675-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | CHEMCOM S.A. (BE) | 2022-12-01 | — | — | US | disclosed |
| EP-4059917-A2 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | ChemCom S.A. (BE) | 2022-09-21 | — | — | EP | disclosed |
| US-11382848-B2 | Compounds reducing malodour perception and the use thereof | CHEMCOM S.A. (BE) | 2022-07-12 | — | — | US | disclosed |
| WO-2018138369-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | CHEMCOM S.A. (BE) | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382848-B2 | Compounds reducing malodour perception and the use thereof | OR51E2, OR10J3, SRD5A1 | NPC1 996/4885RAB9A 3871/4885MAPT 3988/4885 |
| US-20220378675-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | OR51E2, OR10J3, SRD5A1 | NPC1 996/4885RAB9A 3871/4885MAPT 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.