Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424935 | 1.00 | NPC1 (0.49) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL6603490 | 0.81 | TDP1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL3222257 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL10410990 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL3222249 | 0.81 | ALDH1A1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL8948080 | 0.81 | TDP1 (0.62) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380625 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380608 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380623 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 | |
| SCHEMBL31380589 | 0.81 | TP53 (0.44) | NPC1RAB9AMAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710181-A | Compounds for reducing perception of malodour and uses thereof | 凯姆克姆公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-110494413-B | Compounds for reducing perception of malodour and uses thereof | 凯姆克姆公司 | 2022-11-22 | — | — | CN | disclosed |