Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323396 | 0.87 | LTA4H (0.48) | NR4A1NR4A2NR4A3MAOBALOX5 | |
| SCHEMBL3837460 | 0.87 | FFAR1 (0.51) | MAOBALOX5ACACBFFAR1 | |
| SCHEMBL15232863 | 0.85 | KMT2A (0.57) | NR4A2MAOBALOX5 | |
| SCHEMBL1553476 | 0.83 | SYK (0.54) | MAOBALOX5ACACB | |
| SCHEMBL2295812 | 0.82 | HIF1A (0.56) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL2296971 | 0.82 | HIF1A (0.56) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL9537619 | 0.82 | GSK3B (0.49) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL20425137 | 0.82 | PPARG (0.59) | NR4A1NR4A2NR4A3MAOBFFAR1 | |
| SCHEMBL19974547 | 0.81 | FFAR1 (0.54) | NR4A1NR4A2NR4A3MAOBALOX5 | |
| SCHEMBL323593 | 0.81 | BCHE (0.64) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |