Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533724 | 0.85 | SYK (0.51) | ALOX5 | |
| SCHEMBL20425199 | 0.82 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ALOX5MAOB | |
| SCHEMBL27711198 | 0.82 | BCHE (0.58) | BCHE | |
| SCHEMBL1936242 | 0.81 | BCAT2 (0.43) | BCHE | |
| SCHEMBL17386334 | 0.81 | MAOB (0.54) | ALOX5MAOB | |
| SCHEMBL17386331 | 0.81 | MAOB (0.54) | ALOX5MAOB | |
| SCHEMBL28779138 | 0.80 | PPARG (0.52) | NR4A1NR4A2NR4A3ALOX5MAOB | |
| SCHEMBL27875629 | 0.79 | BCHE (0.49) | NR4A1NR4A2NR4A3ALOX5MAOB | |
| SCHEMBL7167442 | 0.79 | ALOX5 (0.49) | ALOX5MAOBBCHE | |
| SCHEMBL19974547 | 0.78 | FFAR1 (0.54) | NR4A1NR4A2NR4A3ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |