Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038341 | 0.82 | MAPT (0.54) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL2044582 | 0.78 | MAPT (0.57) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL2042643 | 0.78 | MAPT (0.50) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL27893661 | 0.78 | GRIN2D (0.49) | KDM4ENPC1PKML3MBTL1 | |
| SCHEMBL25168109 | 0.77 | RAB9A (0.57) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL27597916 | 0.76 | MAPT (0.67) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL25442712 | 0.76 | RAB9A (0.60) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL11593766 | 0.74 | MAPT (0.81) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL6339847 | 0.74 | MAPT (0.69) | MAPTHPGDALDH1A1RAB9AGFER | |
| SCHEMBL2039801 | 0.73 | NOX4 (0.48) | MAPTHPGDALDH1A1RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-02-12 | — | — | US | claimed |
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | claimed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | claimed |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-02-12 | — | — | US | disclosed |
| EP-2516400-B1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2017-03-22 | — | — | EP | disclosed |
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | COLLETTE PATRICE LUCIEN MAURICE (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-11 | — | — | US | disclosed |
| EP-2516400-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077046-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068488-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | MAPT 761/4885HPGD 93/4885ALDH1A1 208/4885 |
| US-20130178633-A1 | PHENOL DERIVATIVES AND THE PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | MAPT 761/4885HPGD 93/4885ALDH1A1 208/4885 |
| US-10202346-B2 | Phenol derivatives and the pharmaceutical or cosmetic use thereof | TYR, MITF, CUTA | MAPT 761/4885HPGD 93/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.