Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 4/20 | 0.40 |
| ▸ | IDH2 | P48735 | 3/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428031 | 0.86 | ADRB1 (0.37) | IDH1IDH2LOXL2LOXADRB1 | |
| SCHEMBL18532095 | 0.85 | ADORA2A (0.34) | — | |
| SCHEMBL20427985 | 0.83 | IDH1 (0.39) | IDH1IDH2MALT1AAK1ADRB1 | |
| SCHEMBL17109750 | 0.81 | MALT1 (0.43) | IDH1IDH2MALT1AAK1LOXL2 | |
| SCHEMBL3295825 | 0.78 | MALT1 (0.47) | IDH1IDH2MALT1LOXL2LOX | |
| Tert-Butanol SCHEMBL28823763 | 0.78 | MALT1 (0.41) | IDH1IDH2MALT1LOXL2ADRB1 | |
| SCHEMBL1118377 | 0.78 | MALT1 (0.41) | IDH1IDH2MALT1AAK1ADRB1 | |
| SCHEMBL18857239 | 0.78 | SYK (0.35) | — | |
| SCHEMBL1118241 | 0.78 | MALT1 (0.45) | IDH1IDH2MALT1AAK1LOXL2 | |
| SCHEMBL23671169 | 0.74 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035790-B2 | RORγ modulators | EXELIXIS, INC. (US) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035790-B2 | RORγ modulators | RORB, RORA, RORC | IDH1 2620/4885IDH2 3019/4885MALT1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.