Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24428718 | 1.00 | PPARA (0.32) | PPARAPPARGGLAACENPC1 | |
| SCHEMBL19830204 | 0.85 | NPC1 (0.32) | PPARAPPARGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14028299 | 0.74 | HSD17B10 (0.43) | GLANPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL24180375 | 0.72 | MAPT (0.39) | PPARAPPARGACESMN1; SMN2HSD17B10 | |
| SCHEMBL28061468 | 0.70 | CYP2C19 (0.51) | GLANPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL20408407 | 0.70 | ACE (0.46) | PPARAPPARGACEMETAP2 | |
| SCHEMBL8483117 | 0.70 | IDO1 (0.42) | TACR1 | |
| SCHEMBL9029161 | 0.67 | TSHR (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL649075 | 0.67 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2 | |
| SCHEMBL11104061 | 0.66 | ADRA2A (0.35) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354644-A1 | CLEAVABLE LIPIDS | Translate Bio, Inc. (US) | 2018-08-01 | — | — | EP | disclosed |