Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162901 | 0.78 | KMT2A (0.44) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL15204826 | 0.78 | KMT2A (0.44) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL20428951 | 0.77 | GRM5 (0.49) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL20429001 | 0.77 | GAA (0.40) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL24130265 | 0.76 | ALDH1A1 (0.39) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL159632 | 0.73 | RAB9A (0.47) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL19886205 | 0.69 | RAB9A (0.43) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL1677251 | 0.69 | NPC1 (0.60) | KMT2AGAAHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL21534725 | 0.69 | PLA2G4A (0.32) | LMNA | |
| SCHEMBL9331208 | 0.68 | HDAC3 (0.46) | KMT2AGAAHSD17B10MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354651-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica N.V. (BE) | 2018-08-01 | — | — | EP | disclosed |