Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906313 | 0.73 | CES1 (0.45) | SMN1; SMN2MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL6905039 | 0.71 | MALT1 (0.38) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL5436534 | 0.71 | TDP1 (0.44) | SMN1; SMN2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL20210303 | 0.70 | CYP2A6 (0.41) | SMN1; SMN2MAPTNPC1CASP3SENP8 | |
| SCHEMBL22313469 | 0.69 | HTR7 (0.42) | SMN1; SMN2MAPTNPC1CASP3SENP8 | |
| SCHEMBL13509013 | 0.69 | MEN1 (0.40) | MAPTTP53MEN1KMT2ALMNA | |
| SCHEMBL6683871 | 0.66 | HTR6 (0.37) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL20210029 | 0.66 | TDP1 (0.39) | SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL20210153 | 0.64 | TDP1 (0.38) | SMN1; SMN2TP53ALDH1A1LMNA | |
| SCHEMBL10042845 | 0.64 | ALDH1A1 (0.46) | MAPTTP53ALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3012261-B1 | METALLOCENE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST COMPOSITION | LG CHEMICAL LTD (KR) | 2018-08-01 | — | — | EP | disclosed |