Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906313 | 0.80 | CES1 (0.45) | HTR6KDM4EMEN1KMT2ALMNA | |
| SCHEMBL6683871 | 0.80 | HTR6 (0.37) | HTR6KDM4EMEN1KMT2ASLC6A2 | |
| SCHEMBL27759205 | 0.79 | ALDH1A1 (0.42) | MALT1KDM4ECYP1A2HTR1APARP1 | |
| SCHEMBL27800890 | 0.77 | ALDH1A1 (0.41) | KDM4ECYP1A2HTR1APARP1HSD17B10 | |
| SCHEMBL6683589 | 0.74 | TAAR1 (0.46) | SIGMAR1 | |
| SCHEMBL28168366 | 0.73 | — | — | |
| SCHEMBL2971557 | 0.72 | TDP1 (0.35) | METAP1ADRA2APARP1ADRA2BADRA2C | |
| SCHEMBL20429136 | 0.71 | SMN1; SMN2 (0.35) | MEN1KMT2ADRD2HTR2AHTR2C | |
| SCHEMBL308273 | 0.70 | HTR6 (0.40) | HTR6KDM4ENFKB1MAOAMAOB | |
| SCHEMBL276262 | 0.70 | MAOA (0.41) | HTR6MEN1KMT2ACYP1A2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689884-B1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-02-16 | — | — | US | disclosed |
| US-20200262943-A1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2020-08-20 | — | — | US | disclosed |
| EP-3689884-A1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND -OLEFIN BY USING SAME | Sabic Sk Nexlene Company Pte. Ltd. (SG) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019064247-A1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND α-OLEFIN BY USING SAME | 사빅 에스케이 넥슬렌 컴퍼니 피티이 엘티디 | 2019-04-04 | — | — | WO | disclosed |
| EP-0923589-B1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-09-15 | — | — | EP | disclosed |
| CN-1114609-C | 3-heteroatom substituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-07-16 | — | — | CN | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| CN-1230190-A | 3-heteroatom sustituted cyclopentadienyl-containing metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | CN | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | ETFB, EMC2, ICMT | MALT1 884/4885HTR6 4177/4885KDM4E 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.