SCHEMBL2042972

SCHEMBL2042972

CCc1c[c]c2c(c1)-c1cc(CC)ccc1C2

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
EIF2AK1 Q9BQI3 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2041292 0.84 CNR1 (0.42) HTR2CHTR2B
SCHEMBL2037143 0.81 SKP2 (0.37) NPC1RAB9AMAPK1SMN1; SMN2HTR2A
SCHEMBL4896965 0.80 ALDH1A1 (0.45) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL20491470 0.72 NPC1 (0.52) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL29090122 0.70 HTR2A (0.42) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL714161 0.70 METAP1 (0.43) RAB9AALDH1A1MAPTSMN1; SMN2HTR2A
SCHEMBL2052784 0.68 METAP1 (0.37) L3MBTL1HTR2AHTR2CHTR2BHPGD
SCHEMBL4894905 0.68 ALDH1A1 (0.46) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL1512594 0.67 ALDH1A1 (0.50) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL27877464 0.67 EIF2AK1 (0.45) NPC1RAB9AALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
CN-106661488-B Syndiotactic propylene polymers and lubricating oils containing the same 埃克森美孚化学专利公司 2021-04-09 CN disclosed
US-10876063-B2 Syndiotactic propylene polymers and lubricating oils comprising the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-12-29 US disclosed
EP-3174961-B1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-11-20 EP disclosed
EP-3174961-A1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME ExxonMobil Chemical Patents Inc. (US) 2017-06-07 EP disclosed
US-20170130159-A1 Syndiotactic Propylene Polymers and Lubricating Oils Comprising the Same EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-11 US disclosed
EP-2516598-B1 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEM PATENTS INC (US) 2016-06-29 EP disclosed
WO-2016018523-A1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-02-04 WO disclosed
US-20140213834-A1 ULTRA HIGH VISCOSITY SYNTHETIC BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-07-31 US disclosed
US-8530712-B2 Process for producing novel synthetic basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-09-10 US disclosed
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-05-23 US disclosed
EP-2516598-A2 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS Exxonmobil Chemical Patents Inc. (US) 2012-10-31 EP disclosed
WO-2011079042-A2 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-06-30 WO disclosed
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131410-A1 Process for Producing Novel Synthetic Basestocks PYM1, SCO2, SPIN4 NPC1 4124/4885RAB9A 4446/4885ALDH1A1 4882/4885
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks PYM1, SPIN4, SCO2 NPC1 4177/4885RAB9A 4118/4885ALDH1A1 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.