Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20491470 | 0.90 | NPC1 (0.52) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL29090122 | 0.88 | HTR2A (0.42) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL4894905 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL27877464 | 0.84 | EIF2AK1 (0.45) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL4886467 | 0.82 | CNR1 (0.55) | ALDH1A1RAB9ANPC1L3MBTL1HTR2A | |
| SCHEMBL5357579 | 0.81 | ALDH1A1 (0.59) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL26778591 | 0.81 | TSHR (0.55) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL1512594 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL28063980 | 0.80 | RAB9A (0.36) | ALDH1A1RAB9ANPC1MAPTLMNA | |
| SCHEMBL28063986 | 0.80 | CYP2A6 (0.56) | ALDH1A1RAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384611-B | A kind of electron donor of Ziegler-Natta catalyst and preparation method thereof | 亚培烯科技（杭州）有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-105669902-A | Novel cycloolefin copolymer catalyst and synthetic method thereof | 魏东初 | 2016-06-15 | — | — | CN | disclosed |
| CN-105384611-A | Electron donor of Ziegler-Natta catalyst and preparation method of electron donor | SUZHOU APAC BIOLOGICAL SCIENCE & TECH CO LTD | 2016-03-09 | — | — | CN | disclosed |
| CN-105348330-A | 3 mono-substituted or 3,6 bis-substituted fluorenyl metalloscene and preparation method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-105330508-A | 3-monosubstituted or 3,6-disubstituted fluorene derivative and preparing method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |
| US-8084559-B2 | Ethylene-vinylcyclohexane copolymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) | 2008-07-03 | — | — | US | disclosed |
| CN-101107260-A | Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer | SUMITOMO CHEMICAL CO (JP) | 2008-01-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161514-A1 | Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer | AOC2, ACSL1, ACSL3 | ALDH1A1 1292/4885RAB9A 1868/4885NPC1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.