SCHEMBL714161

SCHEMBL714161

Cc1c[c]c2c(c1)-c1cc(C)ccc1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.43
ADORA1 P30542 1/20 0.36
ACHE P22303 2/20 0.36
PARP1 P09874 1/20 0.35
PARP10 Q53GL7 1/20 0.35
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP19A1 P11511 2/20 0.31
CYP11B2 P19099 2/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633503 0.77 METAP1 (0.57) METAP1ADORA1ACHEPARP1PARP10
SCHEMBL546147 0.77 METAP1 (0.57) METAP1ADORA1ACHEPARP1PARP10
SCHEMBL22738419 0.73 METAP1 (0.53) METAP1ADORA1ACHEPARP1PARP10
SCHEMBL715824 0.73 MEN1 (0.32) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL2052784 0.72 METAP1 (0.37) METAP1PARP1PARP10HTR2AHTR2C
SCHEMBL21694418 0.71 METAP1 (0.52) METAP1ADORA1ACHEPARP1PARP10
SCHEMBL2047399 0.70 CHEK2 (0.40) METAP1PARP1PARP10HTR2AHTR2C
SCHEMBL715753 0.70 ALDH1A1 (0.35) ALDH1A1GAAMAPTPKMRAB9A
SCHEMBL2042972 0.70 NPC1 (0.35) HTR2AHTR2CKDM4EALDH1A1GAA
SCHEMBL547186 0.68 ALDH1A1 (0.53) METAP1ACHEHTR2CKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113185545-B Benzylamino-containing side arm Shan Maodi quaternary metal complex and application thereof 吉林大学 2022-11-29 CN claimed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
WO-2023081327-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES CHEVRON ORONITE COMPANY LLC (US) 2023-05-11 WO disclosed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
WO-2011079042-A2 PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-06-30 WO disclosed
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks EXXONMOBIL CHEMICAL PATENTS INC. 2011-06-30 US disclosed
US-20110152463-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 US disclosed
EP-2226326-A1 METHOD FOR PRODUCING ORGANIC ALKALI METAL COMPOUND AND METHOD FOR PRODUCING ORGANIC TRANSITION METAL COMPOUND Mitsui Chemicals, Inc. (JP) 2010-09-08 EP disclosed
US-20100093957-A1 METHOD FOR PRODUCING BUTENE-ETHYLENE COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-15 US disclosed
EP-2123685-A1 METHOD FOR PRODUCING BUTENE-ETHYLENE COPOLYMER Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP disclosed
EP-0513380-B1 PROCESS FOR PRODUCING OLEFINIC POLYMER IDEMITSU KOSAN CO (JP) 1997-10-01 EP disclosed
US-5369196-A Production process of olefin based polymers IDEMITSU KOSAN CO., LTD. (JP) 1994-11-29 US disclosed
EP-0513380-A1 PROCESS FOR PRODUCING OLEFINIC POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN METAP1 3183/4885ADORA1 1967/4885ACHE 1754/4885
US-20110160502-A1 Process for Producing Novel Synthetic Basestocks PYM1, SPIN4, SCO2 METAP1 4728/4885ADORA1 4689/4885ACHE 4882/4885
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 METAP1 617/4885ADORA1 4801/4885ACHE 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.