SCHEMBL204302

SCHEMBL204302

NC(=O)c1cccc(OCCCCCCc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.58
PRSS1 P07477 7/20 0.56
SIRT2 Q8IXJ6 1/20 0.55
NR4A2 P43354 1/20 0.55
F2 P00734 1/20 0.54
PLG P00747 1/20 0.54
PRSS2 P07478 1/20 0.54
C1S P09871 1/20 0.54
PRSS3 P35030 1/20 0.54
PLA2G4B P0C869 1/20 0.53
PDE4A P27815 1/20 0.53
PDE4B Q07343 1/20 0.53
PDE4C Q08493 1/20 0.53
PDE4D Q08499 1/20 0.53
NR1H4 Q96RI1 1/20 0.53
OPRM1 P35372 1/20 0.53
OPRD1 P41143 1/20 0.53
OPRK1 P41145 1/20 0.53
KCNH2 Q12809 1/20 0.53
FFAR1 O14842 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202127 1.00 FAAH (0.58) FAAHPRSS1SIRT2NR4A2F2
SCHEMBL204344 0.99 NR4A2 (0.56) FAAHPRSS1SIRT2NR4A2F2
SCHEMBL7451728 0.90 SIRT2 (0.60) PRSS1SIRT2NR4A2F2PLG
SCHEMBL3979585 0.90 PRSS1 (0.65) PRSS1NR4A2F2PLGPRSS2
SCHEMBL9853952 0.88 NR4A2 (0.69) NR4A2PLA2G4BNR1H4FFAR1KMT2A
SCHEMBL203431 0.88 PRSS1 (0.67) PRSS1NR4A2F2PLGPRSS2
SCHEMBL7889295 0.86 PRSS1 (0.56) PRSS1SIRT2NR4A2F2PLG
SCHEMBL7889327 0.86 PRSS1 (0.56) PRSS1SIRT2NR4A2F2PLG
SCHEMBL9853997 0.85 NR4A2 (0.69) NR4A2PLA2G4BNR1H4FFAR1KMT2A
SCHEMBL7896958 0.84 PRSS1 (0.55) PRSS1SIRT2NR4A2F2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 US disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122918-A1 ANTIBACTERIAL AGENTS ALK, ROS1, ARG1 FAAH 2422/4885PRSS1 4371/4885SIRT2 3117/4885
US-20130072520-A2 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 FAAH 2356/4885PRSS1 3674/4885SIRT2 2237/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 FAAH 2031/4885PRSS1 4531/4885SIRT2 2868/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 FAAH 2356/4885PRSS1 3674/4885SIRT2 2237/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 FAAH 2356/4885PRSS1 3674/4885SIRT2 2237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.