Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | PDE5A | O76074 | 7/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834216 | 0.91 | PDE5A (0.46) | KCNH2PDE5AP2RX3DRD1DRD5 | |
| SCHEMBL19374888 | 0.85 | RAB9A (0.35) | PDE5AP2RX3 | |
| SCHEMBL18833734 | 0.81 | P2RX3 (0.40) | PDE5AP2RX3 | |
| SCHEMBL18834480 | 0.77 | TP53 (0.35) | PDE5A | |
| SCHEMBL19375011 | 0.73 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL20431835 | 0.67 | DRD2 (0.30) | — | |
| SCHEMBL13187198 | 0.67 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL29368800 | 0.67 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL19560547 | 0.66 | PDE5A (0.39) | KCNH2PDE5AP2RX3 | |
| SCHEMBL13186660 | 0.66 | KCNH2 (0.98) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |