Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 19/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18833734 | 0.90 | P2RX3 (0.40) | P2RX3ADORA1 | |
| SCHEMBL18834216 | 0.83 | PDE5A (0.46) | P2RX3 | |
| SCHEMBL18834534 | 0.77 | P2RX3 (0.42) | P2RX3 | |
| SCHEMBL18834480 | 0.75 | TP53 (0.35) | — | |
| SCHEMBL20432012 | 0.73 | KCNH2 (0.47) | P2RX3 | |
| SCHEMBL19374860 | 0.70 | LMNA (0.54) | P2RX3 | |
| SCHEMBL21499718 | 0.70 | P2RX3 (0.47) | P2RX3 | |
| SCHEMBL20432487 | 0.69 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL19560547 | 0.68 | PDE5A (0.39) | P2RX3 | |
| SCHEMBL19374888 | 0.68 | RAB9A (0.35) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |