SCHEMBL204353

SCHEMBL204353

CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(Oc2ccccc2F)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
GCK P35557 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.40
MTNR1B P49286 1/20 0.40
PARP10 Q53GL7 1/20 0.39
CXCL8 P10145 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KLF5 Q13887 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR5 Q9H1C0 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358726 1.00 KDM4E (0.43) KDM4ENPC1RAB9AGCKTDP1
SCHEMBL9152513 0.89 KDM4E (0.42) KDM4ERAB9APOLBMTNR1BMEN1
SCHEMBL9152526 0.89 KDM4E (0.42) KDM4ERAB9APOLBMTNR1BMEN1
SCHEMBL30051737 0.89 KDM4E (0.44) KDM4ENPC1RAB9AGCKTDP1
SCHEMBL2858455 0.89 KDM4E (0.44) KDM4ENPC1RAB9AGCKTDP1
SCHEMBL2858451 0.89 KDM4E (0.44) KDM4ENPC1RAB9AGCKTDP1
SCHEMBL9150478 0.89 RAB9A (0.46) KDM4ERAB9ATDP1L3MBTL1POLB
SCHEMBL9150477 0.89 RAB9A (0.46) KDM4ERAB9ATDP1L3MBTL1POLB
SCHEMBL29359491 0.89 KDM4E (0.52) KDM4ENPC1RAB9APOLBMTNR1B
SCHEMBL202624 0.89 KDM4E (0.52) KDM4ENPC1RAB9APOLBMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
CN-111194314-B Microbicidal pyridine amide derivative 先正达参股股份有限公司 2022-12-30 CN disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 WO disclosed
EP-2749167-A1 Formulation for the antimicrobial treatment of polyvinyl chloride compositions Sanitized AG (CH) 2014-07-02 EP disclosed
EP-2670239-A1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS Sanitized AG (CH) 2013-12-11 EP disclosed
EP-0915885-A1 PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION BAYER AG (DE) 1999-05-19 EP disclosed
EP-0865436-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AG (DE) 1998-09-23 EP disclosed
WO-1998004562-A1 PYRAZINE DERIVATIVES AND THEIR USE FOR MATERIAL AND PLANT PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1998-02-05 WO disclosed
WO-1997020830-A1 DITHIAZOLDIOXIDES AND THE USE THEREOF AS MICROBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 WO disclosed
EP-0750542-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AG (DE) 1997-01-02 EP disclosed
EP-0713485-A1 THIOCARBAMOYL COMPOUNDS BAYER AG (DE) 1996-05-29 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995004722-A1 THIOCARBAMOYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1995-02-16 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 KDM4E 1828/4885NPC1 2197/4885RAB9A 2947/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 KDM4E 852/4885NPC1 995/4885RAB9A 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.