Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858451 | 1.00 | KDM4E (0.44) | KDM4EPOLBTDP1L3MBTL1LPAR1 | |
| SCHEMBL30051737 | 1.00 | KDM4E (0.44) | KDM4EPOLBTDP1L3MBTL1LPAR1 | |
| SCHEMBL29358726 | 0.89 | KDM4E (0.43) | KDM4EPOLBTDP1L3MBTL1LPAR1 | |
| SCHEMBL9420381 | 0.89 | KDM4E (0.46) | KDM4EPOLBRAB9ACTNNB1NPSR1 | |
| SCHEMBL204353 | 0.89 | KDM4E (0.43) | KDM4EPOLBTDP1L3MBTL1LPAR1 | |
| SCHEMBL9420378 | 0.89 | KDM4E (0.46) | KDM4EPOLBRAB9ACTNNB1NPSR1 | |
| SCHEMBL2107595 | 0.89 | KDM4E (0.57) | KDM4EPOLBRAB9ANPC1CTNNB1 | |
| SCHEMBL2855935 | 0.89 | KDM4E (0.57) | KDM4EPOLBRAB9ANPC1CTNNB1 | |
| SCHEMBL2107591 | 0.89 | KDM4E (0.57) | KDM4EPOLBRAB9ANPC1CTNNB1 | |
| SCHEMBL2858454 | 0.89 | GCK (0.44) | KDM4EPOLBTDP1L3MBTL1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043600-B2 | Microbiocidal compounds | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-18 | — | — | US | disclosed |
| US-11882834-B2 | Microbiocidal thiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-30 | — | — | US | disclosed |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | SYNGENTA PARTICIPATIONS AG (CH) | 2023-09-05 | — | — | US | disclosed |
| EP-3717479-B1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3941898-B1 | FUNGICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-18 | — | — | US | disclosed |
| EP-3692029-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| EP-3710429-B1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-05 | — | — | EP | disclosed |
| US-6893651-B1 | Synergistic combination of cyclic ketoenol with agonists or antagonists of nicotinic acetylcholine receptors; protecting plants | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-17 | — | — | US | disclosed |
| US-6846777-B2 | Synergistic biocidal composition | THOR GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20040127520-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2004-07-01 | — | — | US | disclosed |
| US-6686387-B2 | SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-20030199490-A1 | Synergistic biocidal composition | THOR GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030092641-A1 | Synergistic insecticidal mixtures | DOW AGROSCIENCES LLC | 2003-05-15 | — | — | US | disclosed |
| US-6444667-B1 | OF SPINOSYNS AND AGONISTS OR ANTAGONISTS OF NICOTINIC ACETYLCHOLINE RECEPTORS FOR PROTECTING PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-5972971-A | WOOD PRESERVATIVE CONSISTS OF A MIXTURE OF METACONAZOLE OR AN ACID ADDITION SALT OR METAL COMPLEX AND IMIDACLOPRID OR SALT OR METAL COMPLEX | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5622546-A | Mould-resistant emulsion paints | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| US-5466693-A | FOE USE IN THE CULTIVATION OF RICE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092641-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885TDP1 4366/4885 |
| US-12043600-B2 | Microbiocidal compounds | MPO, MSR1, PRF1 | KDM4E 2462/4885POLB 3401/4885TDP1 1325/4885 |
| US-20040127520-A1 | Synergistic insecticidal mixtures | CHRM3, ACHE, CHRM2 | KDM4E 3852/4885POLB 4880/4885TDP1 4366/4885 |
| US-11882834-B2 | Microbiocidal thiazole derivatives | MSR1, TLR1, IFNG | KDM4E 3260/4885POLB 3655/4885TDP1 806/4885 |
| US-12012399-B2 | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives | TLR1, TLR5, IDO1 | KDM4E 2885/4885POLB 2340/4885TDP1 1154/4885 |
| US-11629138-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | KDM4E 2969/4885POLB 3534/4885TDP1 1229/4885 |
| US-11744246-B2 | Preparation of mammalian oocyte for fertilization via a soluble human PH20 hyaluronidase polypeptide | PHF20, FUCA1, ZP1 | KDM4E 4050/4885POLB 4375/4885TDP1 1498/4885 |
| US-11629129-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, MSR1 | KDM4E 3192/4885POLB 3215/4885TDP1 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.