Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.78 |
| ▸ | DDX3X | O00571 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | IDH1 | O75874 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955544 | 0.88 | TRPV1 (0.75) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL546131 | 0.88 | TRPV1 (1.00) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL15507203 | 0.86 | MEN1 (0.82) | DDX3XMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29494984 | 0.86 | MEN1 (0.82) | DDX3XMAPTMEN1KMT2AMAPK1 | |
| Urea SCHEMBL2156770 | 0.85 | TRPV1 (0.70) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL6371141 | 0.84 | TRPV1 (0.76) | TRPV1DDX3XMAPTMEN1KMT2A | |
| Urea SCHEMBL2155975 | 0.84 | TRPV1 (0.93) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL11898961 | 0.82 | DDX3X (1.00) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL10192076 | 0.78 | DDX3X (0.84) | TRPV1DDX3XMAPTMEN1KMT2A | |
| SCHEMBL6296073 | 0.77 | MEN1 (0.70) | TRPV1DDX3XMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215705-A1 | hTRPV1 CHEMICAL AGENTS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215705-A1 | hTRPV1 CHEMICAL AGENTS | TRPV1, TRPA1, TRPV4 | TRPV1 1/4885DDX3X 984/4885MAPT 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.