Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ASGR1 | P07306 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241659 | 0.86 | TSHR (0.38) | SMN1; SMN2ASGR1TSHR | |
| SCHEMBL9079148 | 0.85 | ASGR1 (0.34) | SMN1; SMN2ASGR1 | |
| SCHEMBL124555 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2ASGR1TSHRALDH1A1TDP1 | |
| SCHEMBL21019415 | 0.81 | — | — | |
| SCHEMBL214598 | 0.80 | TSHR (0.38) | SMN1; SMN2ASGR1TSHRALDH1A1TDP1 | |
| SCHEMBL11327246 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ASGR1TSHRALDH1A1TDP1 | |
| SCHEMBL16298823 | 0.79 | ASGR1 (0.31) | ASGR1 | |
| SCHEMBL5810223 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2ASGR1ALDH1A1TDP1 | |
| SCHEMBL2902859 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2ASGR1ALDH1A1TDP1 | |
| SCHEMBL10071379 | 0.76 | ALDH1A1 (0.42) | SMN1; SMN2ASGR1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215969-A1 | Fluorene Derivative, Method for Producing the Same, Resin Composition, and Article | KINKI UNIVERSITY (JP) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215969-A1 | Fluorene Derivative, Method for Producing the Same, Resin Composition, and Article | FRG1, F12, FXR1 | SMN1; SMN2 2402/4885ASGR1 1804/4885TSHR 3802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.