Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044587 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAAF2DAO | |
| SCHEMBL2043622 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAF2DAO | |
| SCHEMBL5788690 | 0.72 | LTA4H (0.49) | ALDH1A1KDM4EGAAHTTKMT2A | |
| SCHEMBL2044450 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAF2DAO | |
| SCHEMBL2051564 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAF2DAO | |
| SCHEMBL10919795 | 0.71 | HTT (0.47) | ALDH1A1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL10920829 | 0.71 | HTT (0.47) | ALDH1A1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL13504693 | 0.69 | GRM1 (0.43) | ALDH1A1KMT2AGSK3BTSHR | |
| SCHEMBL11201725 | 0.65 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAF2DAO | |
| SCHEMBL27555390 | 0.64 | BCL2L1 (0.37) | ALDH1A1KDM4EGAAMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516423-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | Bayer CropScience AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076725-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |