SCHEMBL375976

SCHEMBL375976

CCCCCCCCCCCCCCCCO[Si](CC(C)C)(OCCCCCCCCCCCC)OCCC(S)CCCCCCCCCCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20448337 0.85 LPAR3 (0.38) LPAR2LPAR3
SCHEMBL8680466 0.85 LPAR3 (0.38) LPAR2LPAR3
SCHEMBL17686048 0.81 S1PR2 (0.38)
SCHEMBL2336204 0.78 LPAR3 (0.35) LPAR2LPAR3
SCHEMBL2398601 0.77 ADRB2 (0.35)
SCHEMBL375707 0.75 LPAR2 (0.33) LPAR2LPAR3
SCHEMBL375693 0.75 LPAR2 (0.33) LPAR2LPAR3
SCHEMBL375561 0.75 LPAR2 (0.33) LPAR2LPAR3
SCHEMBL16497342 0.74 LMNA (0.35) LPAR2LPAR3
SCHEMBL16496643 0.74 LMNA (0.35) LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 WO disclosed
US-7339067-B2 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2008-03-04 US disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 LPAR2 1773/4885LPAR3 3000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.