Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043293 | 0.82 | HPGD (0.56) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2036868 | 0.82 | MAPT (0.59) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2040082 | 0.81 | KDM4E (0.56) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13198518 | 0.80 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2038512 | 0.78 | RAB9A (0.52) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31311257 | 0.78 | GAA (0.63) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2037443 | 0.78 | MAPT (0.64) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30301294 | 0.77 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL802037 | 0.77 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30520309 | 0.76 | KDM4E (0.59) | MAPTHPGDALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516399-B1 | PHENOLIC DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2018-04-18 | — | — | EP | claimed |
| US-9120753-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-09-01 | — | — | US | claimed |
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-04 | — | — | US | claimed |
| EP-2516399-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077044-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | claimed |
| EP-2516399-B1 | PHENOLIC DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2018-04-18 | — | — | EP | disclosed |
| US-9120753-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-09-01 | — | — | US | disclosed |
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-04 | — | — | US | disclosed |
| EP-2516399-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077044-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | MAPT 775/4885HPGD 90/4885ALDH1A1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.