Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846551 | 0.86 | HTR2A (0.49) | HTR2ATAAR1 | |
| SCHEMBL5917373 | 0.85 | CYP2D6 (0.57) | HTR2ATAAR1 | |
| SCHEMBL5917347 | 0.85 | CYP2D6 (0.57) | HTR2ATAAR1 | |
| SCHEMBL5917351 | 0.85 | CYP2D6 (0.57) | HTR2ATAAR1 | |
| SCHEMBL7530590 | 0.85 | HTR2A (0.50) | HTR2ATAAR1HTR2CP2RX3P2RX2 | |
| SCHEMBL5663639 | 0.85 | CYP2D6 (0.57) | HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL5917339 | 0.84 | MEN1 (0.58) | HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL5917346 | 0.84 | MEN1 (0.58) | HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL5917341 | 0.84 | MEN1 (0.58) | HTR2ATAAR1 | |
| SCHEMBL13748156 | 0.83 | P2RX3 (0.55) | HTR2ATAAR1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2950104-B1 | IMMUNOASSAY FOR COMPOUNDS OF THE NBOME FAMILY | RANDOX LABORATORIES LTD (GB) | 2018-08-08 | — | — | EP | claimed |
| US-11759438-B2 | Compositions and methods for treating ocular pathologies | THE BOARD OF SUPERVISORS OF LOUISIANA STATE (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230277503-A1 | COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-09-07 | — | — | US | disclosed |
| US-20200330405-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR PATHOLOGIES | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2020-10-22 | — | — | US | disclosed |
| US-20200078335-A1 | COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2020-03-12 | — | — | US | disclosed |
| EP-3618850-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR PATHOLOGIES | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2020-03-11 | — | — | EP | disclosed |
| CN-110662549-A | Compositions and methods for treating ocular diseases | 路易斯安娜州立大学监测委员会，农业和机械学院 | 2020-01-07 | — | — | CN | disclosed |
| WO-2018204359-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR PATHOLOGIES | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2018-11-08 | — | — | WO | disclosed |
| WO-2018204354-A1 | COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2018-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330405-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR PATHOLOGIES | HTR1A, KDR, HTR3A | HTR2A 6/4885TAAR1 87/4885HTR2C 53/4885 |
| US-20230277503-A1 | COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS | LTB4R2, LTB4R, CYSLTR1 | HTR2A 7/4885TAAR1 436/4885HTR2C 49/4885 |
| US-20200078335-A1 | COMPOSITIONS AND METHODS TO REDUCE PATHOGENESIS | LTB4R2, LTB4R, CYSLTR1 | HTR2A 7/4885TAAR1 436/4885HTR2C 49/4885 |
| US-11759438-B2 | Compositions and methods for treating ocular pathologies | HTR1A, KDR, HTR3A | HTR2A 6/4885TAAR1 87/4885HTR2C 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.