Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16834202 | 0.84 | ALDH1A1 (0.34) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL17459753 | 0.82 | ALDH1A1 (0.33) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL4866079 | 0.80 | ALDH1A1 (0.32) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6444703 | 0.79 | ALDH1A1 (0.33) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2849490 | 0.77 | ALDH1A1 (0.32) | MAPTALDH1A1POLBHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3253259 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3028477 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL2045225 | 0.75 | EBP (0.31) | EBPDHCR7CRHR1 | |
| Hydrochloric Acid SCHEMBL547963 | 0.75 | — | — | |
| SCHEMBL29489277 | 0.74 | TAS1R3 (0.31) | MAPTALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11565511-B2 | Co-injection molded multilayer structure and method for producing same | KURARAY CO., LTD. (JP) | 2023-01-31 | — | — | US | disclosed |
| US-11383497-B2 | Co-injection-molded multilayer structure | KURARAY CO., LTD. (JP) | 2022-07-12 | — | — | US | disclosed |
| EP-3527370-B1 | CO-INJECTION-MOLDED MULTILAYER STRUCTURE | KURARAY CO (JP) | 2022-03-09 | — | — | EP | disclosed |
| US-20200180279-A1 | CO-INJECTION-MOLDED MULTILAYER STRUCTURE | KURARAY CO., LTD. (JP) | 2020-06-11 | — | — | US | disclosed |
| US-20200086617-A1 | CO-INJECTION MOLDED MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME | KURARAY CO., LTD. (JP) | 2020-03-19 | — | — | US | disclosed |
| EP-3527370-A1 | CO-INJECTION-MOLDED MULTILAYER STRUCTURE | Kuraray Co., Ltd. (JP) | 2019-08-21 | — | — | EP | disclosed |
| US-7771834-B2 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2010-08-10 | — | — | US | disclosed |
| US-7666966-B2 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2010-02-23 | — | — | US | disclosed |
| US-7579404-B2 | Polymerizable composition and molded product thereof | ZEON CORPORATION (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20090042045-A1 | Norbornene-Based Resin Molded Article and the Method of Production Thereof | RIMTEC CORPORATION (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1535941-B1 | PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS | ZEON CORP (JP) | 2007-09-12 | — | — | EP | disclosed |
| US-20070191563-A1 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20060293444-A1 | Polymerizable composition and molded product thereof | ZEON CORPORATION (JP) | 2006-12-28 | — | — | US | disclosed |
| US-20060258828-A1 | Polymerizable composition and molded articles produced by using the same | ZEON CORPORATION (JP) | 2006-11-16 | — | — | US | disclosed |
| US-20060211834-A1 | Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material | ZEON CORPORATION (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060205901-A1 | Crosslinkable resin composition and resin formed body produced therefrom | ZEON CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20060154099-A1 | Multilayer body and method for producing same | ZEON CORPORATION (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1655343-A1 | CROSSLINKABLE RESIN COMPOSITION AND RESIN FORMED BODY PRODUCED THEREFROM | Zeon Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
| EP-1535941-A1 | PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS | ZEON CORPORATION (JP) | 2005-06-01 | — | — | EP | disclosed |
| WO-2001072421-A1 | POLYMER SUPPORTED CATALYSTS FOR OLEFIN METATHESIS | GLAXO GROUP LIMITED (GB) | 2001-10-04 | — | — | WO | disclosed |