SCHEMBL20455822

SCHEMBL20455822

CCSc1ccc(Cl)nc1-c1nc2cc(C(F)(F)F)nc(C#N)c2n1C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ EIF4EBP1 Q13541 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ PSMD14 O00487 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.31
▸ GRM2 Q14416 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ CCR2 P41597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521552 1.00 L3MBTL1 (0.36) L3MBTL1EIF4EBP1LMNAMEN1KMT2A
SCHEMBL20465926 0.90 ALDH1A1 (0.32) L3MBTL1EIF4EBP1LMNAMEN1KMT2A
SCHEMBL20468290 0.89 ALDH1A1 (0.32) L3MBTL1EIF4EBP1LMNAMEN1KMT2A
SCHEMBL29521322 0.89 ALDH1A1 (0.32) L3MBTL1EIF4EBP1LMNAMEN1KMT2A
SCHEMBL29521282 0.87 L3MBTL1 (0.34) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL20465844 0.87 L3MBTL1 (0.34) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL20455826 0.85 L3MBTL1 (0.33) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL29521298 0.85 L3MBTL1 (0.33) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL20468293 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29521486 0.82 DDR1 (0.35) L3MBTL1EIF4EBP1LMNACCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110248941-B Aryl-or heteroaryl-substituted imidazopyridine derivatives and their use as pesticides 拜耳公司 2022-09-06 — — CN disclosed
CN-110248942-B Process for preparing halogenated imidazopyridine derivatives 拜耳公司 2022-04-19 — — CN disclosed
EP-3577114-B1 METHOD FOR THE PREPARATION OF HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AG (DE) 2021-11-10 — — EP disclosed
EP-3577114-B1 METHOD FOR THE PREPARATION OF HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AG (DE) 2021-11-10 — — EP disclosed
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2021-07-27 — — US disclosed
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2021-07-27 — — US disclosed
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-04-01 — — US disclosed
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-04-01 — — US disclosed
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2020-09-15 — — US disclosed
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2020-09-15 — — US disclosed
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-30 — — US disclosed
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-30 — — US disclosed
WO-2018141954-A1 ARYL OR HETEROARYL-SUBSTITUTED IMIDAZO PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141955-A1 PROCESS FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141954-A1 ARYL OR HETEROARYL-SUBSTITUTED IMIDAZO PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141955-A1 PROCESS FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides CYP4X1, CYP1A1, CYP1A2 L3MBTL1 896/4885EIF4EBP1 3067/4885LMNA 1094/4885
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES CYP2F1, CYP2D6, POLR2A L3MBTL1 3330/4885EIF4EBP1 1114/4885LMNA 1284/4885
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives CYP2F1, CYP2D6, POLR2A L3MBTL1 3330/4885EIF4EBP1 1114/4885LMNA 1284/4885
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES CYP4X1, CYP1A1, CYP1A2 L3MBTL1 896/4885EIF4EBP1 3067/4885LMNA 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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