SCHEMBL20455823

SCHEMBL20455823

CCSc1ccc(Br)nc1-c1nc2cc(C(F)(F)F)nc(Cl)c2n1C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ DDR1 Q08345 1/20 0.32
▸ CCR2 P41597 1/20 0.31
▸ NT5E P21589 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521336 1.00 L3MBTL1 (0.33) L3MBTL1LMNANPSR1MEN1KMT2A
SCHEMBL29521456 0.90 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL20468387 0.90 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL20468388 0.88 ALDH1A1 (0.32) ALDH1A1
SCHEMBL29521430 0.88 ALDH1A1 (0.32) ALDH1A1
SCHEMBL29521322 0.85 ALDH1A1 (0.32) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL20468290 0.85 ALDH1A1 (0.32) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL20465940 0.81 ALDH1A1 (0.32) KMT2AALDH1A1
SCHEMBL21930788 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL29521282 0.81 L3MBTL1 (0.34) L3MBTL1LMNANPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110248941-B Aryl-or heteroaryl-substituted imidazopyridine derivatives and their use as pesticides 拜耳公司 2022-09-06 — — CN disclosed
CN-110248942-B Process for preparing halogenated imidazopyridine derivatives 拜耳公司 2022-04-19 — — CN disclosed
EP-3577114-B1 METHOD FOR THE PREPARATION OF HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AG (DE) 2021-11-10 — — EP disclosed
EP-3577114-B1 METHOD FOR THE PREPARATION OF HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AG (DE) 2021-11-10 — — EP disclosed
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2021-07-27 — — US disclosed
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2021-07-27 — — US disclosed
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-04-01 — — US disclosed
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-04-01 — — US disclosed
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2020-09-15 — — US disclosed
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2020-09-15 — — US disclosed
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-30 — — US disclosed
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2020-07-30 — — US disclosed
WO-2018141954-A1 ARYL OR HETEROARYL-SUBSTITUTED IMIDAZO PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141954-A1 ARYL OR HETEROARYL-SUBSTITUTED IMIDAZO PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141955-A1 PROCESS FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed
WO-2018141955-A1 PROCESS FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2018-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10772332-B2 2-(het)aryl-substituted fused heterocycle derivatives as pesticides CYP4X1, CYP1A1, CYP1A2 L3MBTL1 896/4885LMNA 1094/4885NPSR1 455/4885
US-20210094947-A1 METHOD FOR PREPARING HALOGENATED IMIDAZOPYRIDINE DERIVATIVES CYP2F1, CYP2D6, POLR2A L3MBTL1 3330/4885LMNA 1284/4885NPSR1 2206/4885
US-11072609-B2 Method for preparing halogenated imidazopyridine derivatives CYP2F1, CYP2D6, POLR2A L3MBTL1 3330/4885LMNA 1284/4885NPSR1 2206/4885
US-20200236940-A1 2-(HET)ARYL-SUBSTITUTED FUSED HETEROCYCLE DERIVATIVES AS PESTICIDES CYP4X1, CYP1A1, CYP1A2 L3MBTL1 896/4885LMNA 1094/4885NPSR1 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback