Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.39 |
| ▸ | STK16 | O75716 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26484667 | 0.91 | SMN1; SMN2 (0.46) | SMN1; SMN2DRD3ALDH1A1KDM4EFGFR3 | |
| SCHEMBL26406701 | 0.88 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1KDM4EFGFR3HTT | |
| SCHEMBL17660614 | 0.87 | CCR4 (0.44) | SMN1; SMN2HRH3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15703095 | 0.87 | HIF1A (0.51) | HIF1AACHESMN1; SMN2DRD3ALDH1A1 | |
| SCHEMBL14924073 | 0.85 | KDM2B (0.48) | KDM2BSMN1; SMN2CDK4ALDH1A1KDM4E | |
| SCHEMBL17642601 | 0.85 | SMPD3 (0.44) | FLT3EHMT2EHMT1SMPD3SMN1; SMN2 | |
| SCHEMBL14924072 | 0.85 | KDM2B (0.51) | KDM2BSMN1; SMN2ALKALDH1A1KDM4E | |
| SCHEMBL17631428 | 0.84 | GAA (0.47) | FLT3EHMT2EHMT1SMPD3SMN1; SMN2 | |
| SCHEMBL17306128 | 0.83 | ALDH1A1 (0.54) | KDM2BSMN1; SMN2DRD3ALDH1A1KDM4E | |
| SCHEMBL17660577 | 0.82 | DRD2 (0.43) | SMN1; SMN2DRD3ALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253019-B2 | Tank-binding kinase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-10040781-B2 | Tank-binding kinase inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2018-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253019-B2 | Tank-binding kinase inhibitor compounds | TBKBP1, TNKS1BP1, TNKS | KDM2B 2165/4885FLT3 839/4885HIF1A 2431/4885 |
| US-10040781-B2 | Tank-binding kinase inhibitor compounds | TBKBP1, TNKS1BP1, TNKS | KDM2B 2165/4885FLT3 839/4885HIF1A 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.