Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458202 | 0.79 | ATAD2 (0.47) | L3MBTL1LMNANPSR1EEDRBBP4 | |
| SCHEMBL9892918 | 0.78 | LMNA (0.50) | L3MBTL1LMNANPSR1NPC1ALDH1A1 | |
| SCHEMBL20458229 | 0.77 | CNR2 (0.39) | L3MBTL1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL20458254 | 0.77 | GRM5 (0.36) | L3MBTL1LMNANPSR1NR1H3NR1H2 | |
| SCHEMBL16238549 | 0.74 | LMNA (0.55) | L3MBTL1LMNANPSR1NPC1ALDH1A1 | |
| SCHEMBL16238548 | 0.74 | LMNA (0.55) | L3MBTL1LMNANPSR1NPC1ALDH1A1 | |
| SCHEMBL20458171 | 0.70 | L3MBTL1 (0.48) | L3MBTL1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL20458169 | 0.69 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL20458167 | 0.69 | HSD17B10 (0.41) | NR1H3NR1H2 | |
| SCHEMBL20458168 | 0.69 | EPHX2 (0.44) | L3MBTL1NR1H3NR1H2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |