Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458202 | 0.82 | ATAD2 (0.47) | CNR2L3MBTL1HSD17B10EEDRBBP4 | |
| SCHEMBL9892892 | 0.79 | CNR2 (0.53) | CNR2GPR119L3MBTL1SCN4AHSD17B10 | |
| SCHEMBL20458170 | 0.77 | L3MBTL1 (0.36) | L3MBTL1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL20458171 | 0.75 | L3MBTL1 (0.48) | GPR119L3MBTL1NPC1 | |
| SCHEMBL16238373 | 0.74 | CNR2 (0.56) | CNR2L3MBTL1SCN4AHSD17B10SCN5A | |
| SCHEMBL16238371 | 0.74 | CNR2 (0.56) | CNR2L3MBTL1SCN4AHSD17B10SCN5A | |
| SCHEMBL20458254 | 0.73 | GRM5 (0.36) | GPR119L3MBTL1SCN4ANPC1GRM5 | |
| SCHEMBL20458205 | 0.72 | RAB9A (0.50) | L3MBTL1NPC1 | |
| SCHEMBL20458169 | 0.72 | L3MBTL1 (0.45) | CNR2L3MBTL1GRM5 | |
| SCHEMBL20458149 | 0.71 | ALDH1A1 (0.46) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |