Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 3/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458168 | 0.92 | EPHX2 (0.44) | NR1H2NR1H3USP30MEN1KMT2A | |
| SCHEMBL9892820 | 0.79 | NPC1 (0.55) | USP30ARMEN1KMT2ANPC1 | |
| SCHEMBL13257803 | 0.75 | NPC1 (0.60) | USP30ARMEN1KMT2ANPC1 | |
| SCHEMBL16238686 | 0.75 | NPC1 (0.60) | USP30ARMEN1KMT2ANPC1 | |
| SCHEMBL9892925 | 0.71 | NPC1 (0.55) | USP30MEN1KMT2ANPC1EPHX2 | |
| SCHEMBL16583074 | 0.70 | NR1H2 (0.42) | NR1H2NR1H3MEN1KMT2ANPC1 | |
| SCHEMBL16583073 | 0.70 | NR1H2 (0.42) | NR1H2NR1H3MEN1KMT2ANPC1 | |
| SCHEMBL16583076 | 0.70 | NR1H2 (0.42) | NR1H2NR1H3MEN1KMT2ANPC1 | |
| SCHEMBL20458205 | 0.70 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL22470105 | 0.69 | ALDH1A1 (0.42) | USP30MEN1KMT2ANPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |