Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458171 | 0.85 | L3MBTL1 (0.48) | RAB9ANPC1GAAMAPTMEN1 | |
| SCHEMBL9892842 | 0.82 | NPC1 (0.61) | RAB9ANPC1GAAMAPTTP53 | |
| SCHEMBL13257161 | 0.78 | L3MBTL1 (0.61) | RAB9ANPC1MAPTTP53KDM4E | |
| SCHEMBL20458169 | 0.78 | L3MBTL1 (0.45) | MAPTKDM4EKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL16237604 | 0.78 | L3MBTL1 (0.61) | RAB9ANPC1MAPTTP53KDM4E | |
| SCHEMBL20458149 | 0.75 | ALDH1A1 (0.46) | GAAMAPTALDH1A1HPGD | |
| SCHEMBL20458202 | 0.73 | ATAD2 (0.47) | RAB9ANPC1MAPTKDM4EMEN1 | |
| SCHEMBL20458229 | 0.72 | CNR2 (0.39) | NPC1L3MBTL1 | |
| SCHEMBL31053378 | 0.70 | NR1H3 (0.42) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20458248 | 0.70 | NR1H2 (0.41) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |