Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397873 | 0.73 | PKM (0.45) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL8720366 | 0.70 | GRIN1 (0.65) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL12130587 | 0.70 | GRIN1 (0.65) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL9914296 | 0.70 | GRIN1 (0.65) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL12132159 | 0.70 | GRIN1 (0.65) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL510762 | 0.70 | GRIN1 (0.65) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL16730813 | 0.70 | GRIN1 (0.48) | PKMGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL21649312 | 0.70 | — | — | |
| SCHEMBL20458587 | 0.69 | GRIN2D (0.45) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Hydrochloric Acid SCHEMBL866896 | 0.68 | LMNA (0.67) | PKMGRIN1GRIN2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191417-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF SYNUCLEINOPATHIES | SOM INNOVATION BIOTECH, S.A. (ES) | 2021-09-30 | — | — | WO | disclosed |
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | UNIVERSITY OF MASSACHUSETTS | 2020-10-29 | — | — | US | disclosed |
| EP-3189064-B1 | PLATINUM (IV) COMPLEX WITH INCREASED ANTITUMOR EFFICACY | VUAB PHARMA A S (CZ) | 2018-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339596-A1 | FUROXAN-BASED COMPOUNDS AND USES THEREOF | PARK7, HTT, PRDX5 | PKM 1376/4885GRIN1 765/4885GRIN2A 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.