Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933225 | 0.82 | MAPT (0.41) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL22942635 | 0.82 | MAPT (0.41) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL16683593 | 0.78 | CYP1A2 (0.37) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL21886001 | 0.77 | EGFR (0.37) | MAPTHSD17B10TSHRALDH1A1RECQL | |
| SCHEMBL14748441 | 0.77 | TYR (0.37) | HSD17B10 | |
| SCHEMBL15702942 | 0.75 | PTGDR2 (0.46) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL15702941 | 0.75 | CA3 (0.32) | IDO1SLC6A4HSD17B10MAPK1 | |
| SCHEMBL29493203 | 0.75 | IDO1 (0.50) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL1154758 | 0.75 | IDO1 (0.50) | MAPTCYP3A4HIF1AMEN1HPGD | |
| SCHEMBL17752328 | 0.75 | MAPT (0.58) | MAPTCYP3A4HIF1AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2987796-B1 | HALOGEN-SUBSTITUTED BORONOPHTHALIDES FOR THE TREATMENT OF INFECTIONS | ANACOR PHARMACEUTICALS INC (US) | 2018-08-08 | — | — | EP | disclosed |