Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20459459 | 0.82 | MAPT (0.46) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL22942635 | 0.80 | MAPT (0.41) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL29493203 | 0.73 | IDO1 (0.50) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL1154758 | 0.73 | IDO1 (0.50) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL16683593 | 0.73 | CYP1A2 (0.37) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL703030 | 0.72 | CYP3A4 (0.52) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL92968 | 0.72 | CYP3A4 (0.48) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL4574317 | 0.71 | IDO1 (0.43) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL1307331 | 0.71 | IDO1 (0.43) | MAPTIDO1ALOX15HIF1AHPGD | |
| SCHEMBL29825244 | 0.70 | MAPT (0.50) | MAPTIDO1ALOX15HIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | MAPT 1768/4885IDO1 352/4885ALOX15 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.