Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21886001 | 0.78 | EGFR (0.37) | HSD17B10CA2EGFRACHEALOX5 | |
| SCHEMBL15702941 | 0.77 | CA3 (0.32) | HSD17B10 | |
| SCHEMBL20459459 | 0.77 | MAPT (0.46) | HSD17B10 | |
| SCHEMBL15702942 | 0.77 | PTGDR2 (0.46) | HSD17B10 | |
| SCHEMBL1605246 | 0.74 | TYR (0.56) | TYRESR2EGFRALOX5 | |
| SCHEMBL19647527 | 0.74 | TRPA1 (0.41) | — | |
| SCHEMBL21886000 | 0.72 | ALDH1A1 (0.39) | HSD17B10 | |
| SCHEMBL17787354 | 0.72 | KDM4E (0.44) | HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28488202 | 0.72 | TYR (0.54) | TYRESR2EGFRALOX5 | |
| Gentisyl Alcohol SCHEMBL829492 | 0.72 | KLF10 (0.54) | TYRHSD17B10EGFRKLF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |