Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16683598 | 0.80 | MAPT (0.50) | MAPTALDH1A1POLBCYP2C9 | |
| SCHEMBL20459459 | 0.78 | MAPT (0.46) | CYP1A2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL16683594 | 0.76 | KLF10 (0.39) | CYP1A2CYP2D6MAPTKMT2AMEN1 | |
| SCHEMBL16683590 | 0.75 | LMNA (0.45) | MAPTLMNAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL16683597 | 0.73 | ALDH1A1 (0.36) | CYP2D6MAPTLMNAKMT2AMEN1 | |
| SCHEMBL15933225 | 0.73 | MAPT (0.41) | MAPTLMNAKMT2AMEN1HPGD | |
| SCHEMBL22942635 | 0.73 | MAPT (0.41) | MAPTLMNAKMT2AMEN1HPGD | |
| SCHEMBL16683595 | 0.67 | EGFR (0.43) | MAPTKMT2AMEN1HPGDHIF1A | |
| SCHEMBL29493203 | 0.67 | IDO1 (0.50) | CYP1A2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL1154758 | 0.67 | IDO1 (0.50) | CYP1A2MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566289-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9549938-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160228463-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-08-11 | — | — | US | disclosed |
| US-20160206638-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-07-21 | — | — | US | disclosed |
| US-20160184334-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-06-30 | — | — | US | disclosed |
| US-20160151399-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-06-02 | — | — | US | disclosed |
| US-20150119364-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206638-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CYP1A2 1189/4885CYP2D6 1080/4885MAPT 1768/4885 |
| US-20160151399-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CYP1A2 1189/4885CYP2D6 1080/4885MAPT 1768/4885 |
| US-20160228463-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CYP1A2 1189/4885CYP2D6 1080/4885MAPT 1768/4885 |
| US-20160184334-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CYP1A2 1189/4885CYP2D6 1080/4885MAPT 1768/4885 |
| US-20150119364-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | CYP1A2 1189/4885CYP2D6 1080/4885MAPT 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.