Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049604 | 0.82 | SLC5A2 (0.43) | SLC5A1SLC5A2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL21633505 | 0.81 | FAAH (0.34) | BCL2BCL2L1SLC5A1SLC5A2ALDH1A1 | |
| SCHEMBL10932119 | 0.78 | MCL1 (0.35) | MCL1 | |
| SCHEMBL7584267 | 0.77 | MEN1 (0.58) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL7573416 | 0.77 | BCL2 (0.42) | BCL2BCL2L1ALOX5SLC5A2PTPN1 | |
| SCHEMBL9307175 | 0.76 | MEN1 (0.57) | BCL2BCL2L1ALOX5ALDH1A1TSHR | |
| SCHEMBL6270999 | 0.76 | TSHR (0.49) | BCL2BCL2L1ALOX5PTPN1ALDH1A1 | |
| SCHEMBL7572805 | 0.75 | BCL2 (0.40) | BCL2BCL2L1ALOX5PTPN1PTPN2 | |
| SCHEMBL7582814 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRMEN1HPGDKMT2A | |
| SCHEMBL7582708 | 0.73 | MEN1 (0.40) | BCL2BCL2L1ALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883912-B2 | Synthesis of arborescent polymers via controlled inimer-type reversible addition-fragmentation chain transfer (RAFT) polymerization | UNIVERSITY OF AKRON (US) | 2014-11-11 | — | — | US | disclosed |
| US-20110144268-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2011-06-16 | — | — | US | disclosed |
| WO-2010019563-A1 | SYNTHESIS OF ARBORESCENT POLYMERS VIA CONTROLLED INIMER-TYPE REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER (RAFT) POLYMERIZATION | THE UNIVERSITY OF AKRON (US) | 2010-02-18 | — | — | WO | disclosed |